bs-80281C
[Life Science]
YM-155
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:443.30
Formula:C20H19BrN4O3
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml).
Chemical Name:1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide
Formula:C20H19BrN4O3
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml).
Chemical Name:1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide
Description:
A novel small molecule survivin suppressant. YM-155 suppresses expression of survivin (a member of the IAP family) and induced apoptosis in human tumor cell lines at 10 nmol/L with little effect on other IAP or Bcl-2 family members.1 Overcomes erlotinib resistance in EGFR mutation-positive non-small cell lung cancer.2 Induces DNA damage.3 Induces an autophagy-dependent cell death in adenoid cystic carcinoma cells.4
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.