DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:202.68
Formula:C9H14N2O HCl
Purity:>98%
Solubility:Soluble in Water (up to 15 mg/ml)
Chemical Name:3-Methyl-5-(1-methyl-2(S)-pyrrolidinyl)isoxazole hydrochloride
Description:
Agonist at neuronal nicotinic acetylcholine receptors displaying the highest potency at α4β2 and α2β2 subtypes (EC50= approximately 6 and 11 μM, respectively).1 Displays anxiolytic activity in a rat model and was 6-fold more potent than diazepam.2 Reduces distractibility in a primate model3 and may have relevance in attention deficit hyperactivity disorder4. Improves cognition in Alzheimer’s disease patients.5