DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:364.79
Formula:C17H17ClN2O5
Purity:>98%
Solubility:Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 40 mg/ml with warming).
Chemical Name:2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester
Description:
Akt activator. Binds to the pleckstrin homology domain of Akt preventing membrane translocation but paradoxically activating it in the cytosol. Enhances Akt phosphorylation by upstream protein kinases. Suppresses excitotoxicity-induced neuronal death in vitro and in vivo.1 A useful tool for studying the PI3K/Akt axis.2