DATASHEET
Formulation
powder
Storage:
RT
Product Information:
Molecular Weight:189.17
Formula:C10H7NO3
Purity:>98%
Solubility:Soluble in DMSO (up to 20 mg/ml).
Chemical Name:8-Hydroxy-5-quinolinecarboxylic acid
Description:
Inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC50 = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 μM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively1. A broad spectrum 2-oxoglutarate oxygenase inhibitor which may be used to study hypoxic signaling1. Cell permeable