bs-80248C
[Life Science]
Gue1654
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:447.6
Formula:C23H17N3OS3
Purity:>98%
Solubility:Soluble in DMSO (up to 40 mg/ml with warming).
Chemical Name:N-[7-(Methylthio)benzo[1,2-d:4,3-d']bisthiazol-2-yl]-α-phenylbenzeneacetamide
Formula:C23H17N3OS3
Purity:>98%
Solubility:Soluble in DMSO (up to 40 mg/ml with warming).
Chemical Name:N-[7-(Methylthio)benzo[1,2-d:4,3-d']bisthiazol-2-yl]-α-phenylbenzeneacetamide
Description:
Gue1654 is a biased antagonist for the oxoeicosanoid receptor 1 (OXE-R, GPR170)1, the receptor for 5-Oxo-ETE, a proinflammatory eicosanoid2. It selectively inhibits Gβγ but not Gαi signaling upon activation of the Gαi-βγ heterotrimer by OXE-R1,3. Gue1654 alleviated coronary artery ligation-induced ischemic myocardial injury in a mouse model4.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.