bs-80247C [Life Science]
BRD-7389
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Formulation powder

Storage: -20°C

Product Information:

Molecular Weight:366.42

Formula:C24H18N2O2

Purity:>98%

Solubility:Soluble in DMSO (up to 35 mg/ml).

Chemical Name:1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinolone-2,7-dione

Description:

Inhibits p90 ribosomal S6 kinase (RSK), IC50 = 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively1. Induces a beta-cell-like state in pancreatic apha-cells and induces insulin expression1,2. Increases the endocrine cell content and function of donor human pancreatic islets in culture1. Blocks muscarinic acetylcholine receptor-stimulated RSK activation and subsequent proliferation of SNU-407 colon cancer cells3.

Size: 5 mg, 25 mg5 mg, 25 mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.