bs-80242C
[Life Science]
BMS-303141
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:424.30
Formula:C19H15Cl2NO4S
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml with warming)
Chemical Name:3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1’-biphenyl]-3-yl)-benzenesulfonamide
Formula:C19H15Cl2NO4S
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml with warming)
Chemical Name:3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1’-biphenyl]-3-yl)-benzenesulfonamide
Description:
Potent and selective ATP citrate lyase (ACL) inhibitor, IC50=0.13 M. Inhibits lipid biosynthesis, IC50=8 M in HepG2 cells.1,2 Reduces weight gain, lowers plasma cholesterol, triglycerides and glucose in high-fat-fed mice.2 A novel tool compound for exploring the potential of ACL inhibition as a target for metabolic disorders such as obesity and dyslipidemia.2 Impairs proliferation or induces death in androgen-depleted castration resistant prostate cancer cells.3 Reduces cell cycle progression in iBN cells.4
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.