bs-80240C
[Life Science]
Importazole
DATASHEET
Formulation powder
Storage: RT
Product Information:
Molecular Weight:318.43
Formula:C20H22N4
Purity:>98%
Solubility:Soluble in DMSO (up to 10 mg/ml).
Chemical Name:N-(1-Phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amine
Formula:C20H22N4
Purity:>98%
Solubility:Soluble in DMSO (up to 10 mg/ml).
Chemical Name:N-(1-Phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amine
Description:
Specifically inhibits importin-β-mediated nuclear import without disrupting transportin-mediated nuclear import or CRM1-mediated nuclear export1. When added to cells during mitosis it impairs the release of an importin- cargo probe and causes defects in spindle assembly. Inhibition of importin-β function is most likely mediated by blocking its interaction with RanGTP. It is an important new tool to probe the function of the importin-/RanGTP pathway2-4. Cell permeable
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.