DATASHEET
Formulation
powder
Storage:
RT
Product Information:
Molecular Weight:304.44
Formula:C15H16N2OS2
Purity:>98%
Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 14 mg/ml with warming).
Chemical Name:6,7-Dihydro-3-phenyl-2-(propylthio)thieno[3,2-d]pyrimidin-4(3H)one
Description:
A potent and selective inhibitor of phosphodiesterase PDE11 (IC50=0.28 μM).1 IC50s for PDE1-10 are greater than 100 μM. Restores the ability of p54nrb / NONOKD cells to generate cAMP in response to ACTH stimulation and the production of cortisol and DHEA in response to cAMP signaling.2