bs-80234C
[Life Science]
LM22A-4
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:339.35
Formula:C15H21N3O6
Purity:>98%
Solubility:Soluble in DMSO (up to 50 mg/ml), or in Water (up to 50 mg/ml).
Chemical Name:N,N’N’ Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide
Formula:C15H21N3O6
Purity:>98%
Solubility:Soluble in DMSO (up to 50 mg/ml), or in Water (up to 50 mg/ml).
Chemical Name:N,N’N’ Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide
Description:
Small molecule BDNF mimetic displaying neurotrophhic activity. Partial agonist at TRKB and activates TRKB signaling. In in vitro models of neurodegenerative disease, it prevented neuronal degeneration with equal efficacy to that of BDNF. After in vivo administraton, it caused hippocampal and striatal TrkB activation in mice and improved motor learning after traumatic brain injury in rats1. Improves respiratory function in a mouse models of Rett syndrome2.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.