DATASHEET
Formulation
powder
Storage:
RT
Product Information:
Molecular Weight:160.17
Formula:C6H12N2O3
Purity:>98%
Solubility:Soluble in DMSO (up to 50 mg/ml), or in Water (up to 20 mg/ml with warming).
Chemical Name:1-(2,2-Dimethylhydrazide)butanedioic acid
Description:
A selective inhibitor of the KDM2/7 JmjC subfamily of histone demethylases. IC50=1.5, 0.55 and 2.1 μM for KDM2A, PHF8 and KDM7A respectively. Highly selective over other subfamily members (KDM3, KDM4, KDM5 and KDM6) as well as other 2-oxoglutarate oxygenases (FIH, PHD2 and BBOX1), IC50>100 μM1.