bs-80230C [Life Science]
LYS6K2
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Formulation powder

Storage: RT

Product Information:

Molecular Weight:445.42

Formula:C21H19F4N7

Purity:>98%

Solubility:Soluble in DMSO (up to 1 mg/ml) or in DMF (up to 3 mg/ml).

Chemical Name:4-(4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazol-2-yl)piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine

Description:

A selective inhibitor of the p70 ribosomal S6 kinase (S6K)1. Blocks the phosphorylation of S6 at concentrations as low as 0.1-0.3 μM with no activity at GSK3β and Erk1/2 at 10 μM2. Useful tool to dissect insulin receptor signaling pathways and was employed to show that the action of mTORC1 on SREB P-1c expression is not mediated by S6K2. Cell permeable.

Size: 5 mg, 25 mg5 mg, 25 mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.