DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:339.86
Formula:C21H21NO · HCl
Purity:>98%
Solubility:Soluble in DMSO (up to 8 mg/ml).
Chemical Name:3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride
Description:
A pan-specific ubiquitin isopeptidase inhibitor. (IC50= 45, 37 and 9.8 μM for USP2, USP7 and SENP2 respectively) Does not effect proteasome proteolytic activity. Induces apoptosis via a Bcl-2-dependent but apoptosome-independent mitochondrial pathway1,2. Cell permeable.