bs-80224C
[Life Science]
Indirubin
DATASHEET
Formulation powder
Storage: RT
Product Information:
Molecular Weight:262.3
Formula:C16H10N2O2
Purity:>98%
Solubility:Soluble in DMSO (up to 10 mg/ml).
Chemical Name:3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one
Formula:C16H10N2O2
Purity:>98%
Solubility:Soluble in DMSO (up to 10 mg/ml).
Chemical Name:3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one
Description:
Natural product that acts as an inducer of human AhR-dependent gene expression with 10-fold greater potency over the endogenous agonist TCDD1. Indirubin also inhibits CDKs (IC50 = 50–100 nM) and GSK-3β (IC50 = 5-50 nM)2. Ameliorates the effects of a high-fat diet on mice3. Breaks the inflammatory cycle in in vitro and in vivo models of psoriasis4. Inhibits angiogenesis and causes autophagy and apoptosis in cancer cells5,6.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.