bs-80221C
[Life Science]
AG-1517 HCl
DATASHEET
Formulation powder
Storage: RT
Product Information:
Molecular Weight:360.21
Formula:C16H14BrN3O2
Purity:>98%
Solubility:Soluble in DMSO (up to 5 mg/ml).
Chemical Name:4-(3-Bromoanilino)-6,7-dimethoxyquinazoline hydrochloride
Formula:C16H14BrN3O2
Purity:>98%
Solubility:Soluble in DMSO (up to 5 mg/ml).
Chemical Name:4-(3-Bromoanilino)-6,7-dimethoxyquinazoline hydrochloride
Description:
An ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFRK), with an IC50 of 25 pM. Inhibits other tyrosine kinases at micromolar or higher concentrations. It selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression and oncogenic transformation1. Inhibits the growth of a number of cancer cell lines2. An extremely useful tool for exploring EGF-mediated cellular signaling3.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.