bs-80208C
[Life Science]
SMI-4a
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:273.23
Formula:C11H6F3NO2S
Purity:>98%
Solubility:Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 40 mg/ml with warming).
Chemical Name:5-(3-Trifluoromethylbenzylidene)thiazolidine
Formula:C11H6F3NO2S
Purity:>98%
Solubility:Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 40 mg/ml with warming).
Chemical Name:5-(3-Trifluoromethylbenzylidene)thiazolidine
Description:
A selective, ATP-competitive inhibitor of the Pim protein kinases (IC50 = 24 and 100 nM for Pim-1 and Pim-2 respectively). Selective over a panel of ~50 other kinases1. Induces cell cycle arrest in leukemia and prostate cancer cells2. Blocks the growth of a wide range of myeloid and lymphoid cell lines with precursor T-cell lymphoblastic leukemia/lymphoma (pre-T-LBL/T-ALL) being highly sensitive3. A useful tool for exploring the involvement of Pim in cellular signaling4. Cell permeable.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.