bs-80204C
[Life Science]
Wiskostatin
DATASHEET
Formulation powder
Storage: RT
Product Information:
Molecular Weight:426.15
Formula:C17H18Br2N2O
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 10 mg/ml).
Chemical Name:1-(3,6-Dibromocarbazol-9-yl)-3-dimethylaminopropan-2-ol
Formula:C17H18Br2N2O
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 10 mg/ml).
Chemical Name:1-(3,6-Dibromocarbazol-9-yl)-3-dimethylaminopropan-2-ol
Description:
A selective, reversible inhibitor of neural Wiskott-Aldrich syndrome protein (N-WASP) activity1. Binds to the regulatory domain of N-WASP and inhibits activation of Arp2/3 complex by forcing N-WASP into an inactive conformation2. Inhibits PIP2-induced actin polymerization (EC50=4 μM). Perturbs agrin-elicited acetylcholine receptor clustering3. Inhibits the formation of dendritic spines and synapses in hippocampal neurons4.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.