DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:401.56
Formula:C19H35N3O4S
Purity:>98%
Solubility:Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 5 mg/ml).
Chemical Name:N-Acetyl-Leu-Leu-Methional
Description:
Cell-permeable, peptide aldehyde inhibitor of calpain (calpain I, Ki = 120 nM, calpain II, Ki = 230 nM) and other neutral cysteine proteases. Potent inhibitor of cathepsin L (Ki=0.6 nM) and cathepsin B (Ki=100 nM).1 Weak inhibitor of the chymotrypsin-like activity of the proteasome.2 Cell permeable.