bs-80198C [Life Science]
Aristolochic acid (A&B)
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Formulation powder

Storage: RT

Product Information:

Molecular Weight:341.3 and 311.3

Formula:C17H11NO7 and C16H9NO6

Purity:>98%

Solubility:Soluble in DMSO (up to 30 mg/ml)

Chemical Name:8-Methoxy-6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid (A) and 6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid (B)

Description:

Phytochemical that acts as an anti-inflammatory and phospholipase A2 (PLA2) inhibitor (IC50 = 40 µM in human neutrophils)1. Its mutagenic properties cause tumorigenesis and kidney damage in rodent models and in humans2,3. Induces NF-κB, TGF-β, and oxidative stress in mouse kidney, and mitochondrial apoptosis in rat liver4,5.

Size: 20 mg, 100 mg20 mg, 100 mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.