bs-80196C
[Life Science]
b-AP15 (NSC-687852)
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:419.40
Formula:C22H17N3O6
Purity:>98%
Solubility:Soluble in DMSO (up to 35 mg/ml).
Chemical Name:3,5-bis[(4-Nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one
Formula:C22H17N3O6
Purity:>98%
Solubility:Soluble in DMSO (up to 35 mg/ml).
Chemical Name:3,5-bis[(4-Nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one
Description:
Abrogates the deubiquitinating activity of the 19S regulatory particle by inhibiting ubiquitin C-terminal hydrolase 5 (UCHL5) and ubiquitin-specific peptidase 14 (USP14) resulting in accumulation of polyubiquitin in cells. b-AP15 induces tumor cell apoptosis and tumor progression in four different solid tumor models in vivo.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.