bs-80191C
[Life Science]
24(S)-hydroxycholesterol
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:402.7
Formula:C27H46O2
Purity:>98%
Solubility:Soluble in DMSO (up to 10 mg/ml with warming) or in Ethanol (up to 10 mg/ml).
Chemical Name:Cholest-5-ene-3β,24S-diol
Formula:C27H46O2
Purity:>98%
Solubility:Soluble in DMSO (up to 10 mg/ml with warming) or in Ethanol (up to 10 mg/ml).
Chemical Name:Cholest-5-ene-3β,24S-diol
Description:
Metabolite of cholesterol produced in the brain by the action of CYP46A1 thereby regulating brain cholesterol homeostasis1. Endogenous agonist for the nuclear receptor LXR2. Cerebrospinal fluid content of 24(S)-hydroxycholesterol is reduced in Alzheimer’s disease patients3. Induces RIPK1-dependent necrosis-like cell death in the absence of caspase-84.
Size: 1 mg, 5 mg 5 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.