bs-80189C
[Life Science]
C16
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:268.30
Formula:C13H8N4OS
Purity:>98%
Solubility:Soluble in DMSO (up to 15 mg/ml, with warming).
Chemical Name:6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one
Formula:C13H8N4OS
Purity:>98%
Solubility:Soluble in DMSO (up to 15 mg/ml, with warming).
Chemical Name:6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one
Description:
Inhibits RNA-dependent protein kinase (PKR, IC50 = 210 nM)1. Inhibits ER stress-induced neuronal damage2. Reduces brain PKR activation in vivo3. Prevents apoptosis and IL-1β production in an acute excitotoxic and neuroinflammatory rat model4. Prevents β-amyloid peptide-induced inflammation in primary murine mixed co-cultures5. Cell permeable.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.