bs-80161C
[Life Science]
CHIR-99021
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:465.35
Formula:C22H18Cl2N8
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml).
Chemical Name:6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Formula:C22H18Cl2N8
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml).
Chemical Name:6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Description:
Potent and selective inhibitor of glycogen synthase kinase-3β (GSK3β, IC50 = 5 nM) and GSK3α (IC50 = 10 nM)1. Induces osteoblastogenesis, increases mineralization and inhibits adipogenesis in ST2 cells2. Promotes replication and survival of pancreatic beta cells3. Enhances differentiation and reduces proliferation of adult human olfactory epithelium neural precursors4. Cell permeable and active in vivo.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.