bs-80157C
[Life Science]
Cytarabine
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:243.2
Formula:C9H13N3O5
Purity:>98%
Solubility:Soluble in DMSO (up to 12 mg/ml), or in Water (up to 24 mg/ml).
Chemical Name:4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone
Formula:C9H13N3O5
Purity:>98%
Solubility:Soluble in DMSO (up to 12 mg/ml), or in Water (up to 24 mg/ml).
Chemical Name:4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone
Description:
A nucleoside analog that interferes with DNA synthesis and transcription, particularly in tumor cells1,2. Cellular enzymes convert it to its phosphorylated form, Ara-CTP, which disrupts DNA and RNA synthesis when polymerases attempt to incorporate it3,4. For the same reasons, it is also employed as an antiviral5. It inhibits proliferation of a variety of leukemic cell lines (IC50s 16-72 nM), but is used primarily against acute myeloid leukemia (AML)6,7.
Size: 500 mg, 2 g500 mg, 2 g
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.