bs-80131C
[Life Science]
IU1
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:300.38
Formula:C18H21FN2O
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml).
Chemical Name:1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone
Formula:C18H21FN2O
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml).
Chemical Name:1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone
Description:
Selective inhibitor of Usp14 (IC50<4 μM). Enhances proteasome activity and substrate proteolysis.1,2 Inhibits Dengue virus replication.3 In prion-infected CAD5 cells activation of the ubiquitin proteasome system by IU1 is sufficient to induce clearance of polyubiquitinated substrates and reduce misfolded prion protein load.4 Attenuates ischemia/reperfusion-induced neuronal injury in a mouse model.5 Cell permeable.
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.