DATASHEET
Formulation
Oil
Storage:
-80°C
Product Information:
Molecular Weight:371.56
Formula:C24H37NO2
Purity:>98%
Solubility:Soluble in DMSO (up to 35 mg/ml).
Chemical Name:N-Docosahexaenoylethanolamide
Description:
Anandamide-like lipid mediator produced from DHA in the brain. Stimulates neurite growth, synaptogenesis and glutamatergic synaptic activity in developing hippocampal neurons at 10-100 nM.1 Potently induces neuronal differentiation of neural stem cells.2 Promotes growth of cortical axons vial modulation of hedgehog signaling.3 Binds to and activates orphan receptor GPR110, stimulating cAMP production at low nM concentrations.4 Reduces LPS-induced TNFα production in cultured microglia cells and ameliorates LPS-induced neuroinflammation in a mouse model.5