DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:254.25
Formula:C15H10O4
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 6 mg/ml).
Chemical Name:7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one
Description:
A selective TrkB agonist (Kd=320 nM) with potent neurotrophic activity.1,2 Significantly improves motor deficits, ameliorates brain atrophy and extends survival in the well-characterized N171-82Q Huntington’s disease mouse model.3 Post-traumatic brain injury-treatment promotes neurogenesis in the hippocampus in a mouse model.4 Improves motor performance and motor neuronal survival in an ALS mouse model.5