bs-80109C
[Life Science]
KB-R7943 mesylate
DATASHEET
Formulation powder
Storage: RT
Product Information:
Molecular Weight:427.49
Formula:C16H17N3O3S ∙ CH3SO3H
Purity:>98%
Solubility:Soluble in DMSO (up to 50 mg/ml).
Chemical Name:2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothioures mesylate
Formula:C16H17N3O3S ∙ CH3SO3H
Purity:>98%
Solubility:Soluble in DMSO (up to 50 mg/ml).
Chemical Name:2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothioures mesylate
Description:
KB-R7943 is a potent and selective inhibitor of the reversed Na+/Ca2+ exchanger (NCE or NCX; IC50’s = 1.2-2.4 µM in cardiomyocytes, smooth muscle cells, NCX1-transfected fibroblasts1; 0.7µM in cultured rat forebrain2). KB-R7943 has also been shown to inhibit the mitochondrial Ca2+ uniporter (MCU) – Ki = 5.5 µM.3 Recently shown to inhibit complex I in the mitochondrial respiratory chain (IC50 = 11.4 µM) and block NMDA receptors (IC50 = 13.4 µM).4
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.