bs-80105C
[Life Science]
2-Chloroadenosine
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:301.7
Formula:C10H12ClN5O4
Purity:>95%
Solubility:Soluble in DMSO (up to 30 mg/ml) or in Water (up to 7 mg/ml).
Chemical Name:6-Amino-2-chloropurine riboside
Formula:C10H12ClN5O4
Purity:>95%
Solubility:Soluble in DMSO (up to 30 mg/ml) or in Water (up to 7 mg/ml).
Chemical Name:6-Amino-2-chloropurine riboside
Description:
A metabolically stable adenosine analog that acts as an agonist at A1, A2a, and A3 adenosine receptors (Ki = 300, 80, 1900 nM)1. 2-Chloroadenosine is also a bidirectional substrate for equilibrative nucleoside transporter 4 (ENT4) in acidic conditions2. At 100 µM, it causes accumulation of cAMP in neonatal mouse osteoblast-like cells3. Reduces intracellular ATP levels through both ATP consumption and AMP deamination, and induces apoptosis in leukemic B-cells and rheumatoid fibroblasts4,5.
Size: 50 mg, 250 mg50 mg, 250 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.