bs-80082C
[Life Science]
AP-18
DATASHEET
Formulation powder
Storage: RT
Product Information:
Molecular Weight:209.67
Formula:C11H12ClNO
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
Chemical Name:4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime
Formula:C11H12ClNO
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
Chemical Name:4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime
Description:
TRPA1 channel blocker IC50=3.1-4.5 µM in various cell lines. Reduces cinnamaldehyde-induced nociception in vivo and blocks cold- and mustard oil-induced activation of mouse TRPA1 but not capsaicin-induced activation. Does not block TRPV1, V2, V3, V4 or M8 at concentrations up to 50 µM1. Blocks TRPA1 pore dilation (IC50=10.3 µM)2. An important tool for assessing the role of TRPA1 in cell signaling and physiological processes3-5.
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.