bs-80068C
[Life Science]
Sivelestat
DATASHEET
Formulation powder
Storage: RT
Product Information:
Molecular Weight:456.45
Formula:C20H21N2O7
Purity:>98%
Solubility:Soluble in DMSO (up to 20 mg/ml).
Chemical Name:N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine sodium
Formula:C20H21N2O7
Purity:>98%
Solubility:Soluble in DMSO (up to 20 mg/ml).
Chemical Name:N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine sodium
Description:
Potent and selective leukocyte elastase inhibitor, IC50 = 44 nM1. Displays no activity at a variety of other proteases. Inhibits NF-κB activation2 and LTB4-induced neutrophil migration in vitro3. Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo4.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.