bs-80047C
[Life Science]
Mirin
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:220.3
Formula:C10H8N2O2S
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml).
Chemical Name:2-Amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone
Formula:C10H8N2O2S
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml).
Chemical Name:2-Amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone
Description:
Mirin is an inhibitor of the Mre11/Rad50/Nbs1 (MRN) complex which functions as a DNA damage sensor and activates ataxia-telangiectasia mutated kinase (ATM), a DNA repair enzyme1. Mirin blocks the 3’ and 5’ exonuclease activity of Mre112. It enhances the killing of glioblastoma cells after treatment with alkylating agents such as lomustine3. A very useful tool for determining the involvement of Mre11 in DNA damage response4,5.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.