DATASHEET
Formulation
powder
Storage:
RT
Product Information:
Molecular Weight:264.3
Formula:C14H20N2O3
Purity:>98%
Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 2 mg/ml).
Chemical Name:Suberoylanilide-hydroxamic acid
Description:
Potent and selective histone deacetylase inhibitor1. Induces apoptosis in a variety of tumor cell lines (IC50 = 3-8 µM)2. Synergizes with kinase inhibitors to kill CNS tumor cells3. Prevents diabetes in a mouse model by immunoregulation and β-cell protection4. Induces neuronal differentiation in DKFZ-EP1NS cells, a cell line which displays stem cell features such as self-renewal capacity5. Neurotrophic acitivity6. Cell permeable.