DATASHEET
Formulation
powder
Storage:
RT
Product Information:
Molecular Weight:357.80
Formula:C19H16ClNO4
Purity:>98%
Solubility:Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 2 mg/ml).
Chemical Name:5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide
Description:
Potent, selective inhibitor of the TTX-resistant voltage-gated sodium channel Nav1.8. Nav1.8 is preferentially expressed in sensory neurons, and inhibition attenuates both inflammatory and neuropathic pain in a variety of animal models. IC50's for rat and human Nav1.8 are 140 nM and 8.0 nM respectively.