bs-80019C
[Life Science]
GW-5074
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:520.95
Formula:C15H8Br2INO2
Purity:>98%
Solubility:Soluble in DMSO (up to 50 mg/ml).
Chemical Name:3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodo-1,3-dihydroindol-2-one
Formula:C15H8Br2INO2
Purity:>98%
Solubility:Soluble in DMSO (up to 50 mg/ml).
Chemical Name:3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodo-1,3-dihydroindol-2-one
Description:
Potent inhibitor of cRAF1 kinase (IC50 = 9 nM). Displays 100-fold selectivity for cRAF1 over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. Displays neuroprotective effects In vivo via a mechanism that is independent of MEK, ERK, and Akt signaling. Cell permeable.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.