bs-80018C
[Life Science]
ZM-336372
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:389.46
Formula:C23H23N3O3
Purity:>98%
Solubility:Soluble in DMSO (up to 50 mg/ml).
Chemical Name:3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]benzamide
Formula:C23H23N3O3
Purity:>98%
Solubility:Soluble in DMSO (up to 50 mg/ml).
Chemical Name:3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]benzamide
Description:
Potent and specific inhibitor of the protein kinase c-Raf (IC50=70nM). Has no significant effect on many other protein kinases tested (even at 50µM) with the exception of p38 (SAPK2α) (IC50=2µM) and SAPK2β (p38β) (IC50=2µM). Induces a paradoxical >100-fold activation of c-Raf in whole cells. Induces apoptosis in a variety of cell lines. Cell permeable.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.