bs-80013C
[Life Science]
BML-277
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:363.81
Formula:C20H14ClN3O2
Purity:>98%
Solubility:Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).
Chemical Name:2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide
Formula:C20H14ClN3O2
Purity:>98%
Solubility:Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).
Chemical Name:2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide
Description:
Potent selective inhibitor of Chk2 (IC50 = 15 nM). BML-277 has been screened against a panel of 35 kinases, and shows less that 25% inhibition of any other kinase at 10 µM, demonstrating the selectivity1. Also displays radioprotective activity, preventing apoptosis in human T-cells that were subjected to ionizing radiation (EC50 = 3.0 – 7.6 µM).
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.