bs-7685R [Primary Antibody]
Corin Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Corin

Immunogen Range: 165-245/1042


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 10699

Swiss Prot: Q9Y5Q5

Source: KLH conjugated synthetic peptide derived from human Corin

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 115


Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Dog
Pig
Horse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Sari, Agnes Rosarina Prita, et al. "Characterization of ovine dermal papilla cell aggregation." International Journal of Trichology 8.3 (2016): 121.Read more>>
  • Miyazaki, Jun, et al. "Increased levels of soluble corin in pre-eclampsia and fetal growth restriction." Placenta (2016).Read more>>
  • Miyazaki et al. Increased levels of soluble corin in pre-eclampsia and fetal growth restriction. (2016) Placenta. 48:20-25Read more>>
VALIDATION IMAGES

Antigen: bs-7685P, 0.2ug/100ul \nPrimary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; \nSecondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000;\nTMB staining;\nRead the data in MicroplateReader by 450