bs-75885C

DATASHEET

Formulation Powder

Storage: Stable for 2 years after receipt when stored at -20°C.

Product Information:

CAS Number: 578-74-5

Molecular formula: C21H20O10

Molecular weight: 432.38

Purity: >97% (HPLC)

Appearance: Light yellow powder.

Solubility: Soluble in DMSO (5mg/ml) or DMF.

InChiKey: KMOUJOKENFFTPU-QNDFHXLGSA-N

SMILES: O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC2=CC(OC(C3=CC=C(O)C=C3)=CC4=O)=C4C(O)=C2)[C@@H]1O

Description:

Apigenin 7-glucoside is a flavonoid with anti-inflammatory, antioxidant, anticancer, anti-adipogenic and anxiolytic activities. It has been shown to inhibit LPS-induced nitric oxide production in RAW 264.7 cells or have hepatoprotective activity due to it's antioxidant activities, acting as scavengers of ROS. Apigenin 7-glucoside has been shown to have anti-proliferative activity, possible through cell cycle inhibition and consequently induce apoptosis. it also has the ability to enhance melanogenesis synthesis and tyrosinase activity of B16F10 melanoma cells. Apigenin 7-glucoside has shown neuroprotective effects possibly by inhibiting neuroinflammation and its antioxidant activity. Apigenin-7-O-glucoside inhibits adipogenesis of 3T3-L1 preadipocytes at early stage of adipogenesis at high concentrations, by downregulating PPARgamma and CEBP-alpha.