bs-75882C

DATASHEET

Formulation Powder

Storage: Stable for 2 years after receipt when stored at RT.

Product Information:

CAS Number: 137-66-6

Molecular formula: C22H38O7

Molecular weight: 414.53

Purity: >95%

Appearance: Light yellow powder.

Solubility: Soluble in DMSO (30mg/ml), DMF (30mg/ml) or ethanol (10mg/ml).

InChiKey: QAQJMLQRFWZOBN-UWJYYQICSA-N

SMILES: OC1=C(O)C(O[C@@]1([H])[C@H](COC(CCCCCCCCCCCCCCC)=O)O)=O

Description:

Ascorbic acid 6-palmitate is fat-soluble form of vitamin C formed from ascorbic acid and palmitic acid and not naturally found in food sources. It is used as a source of vitamin C and as food preservative (E number E304) for stabilization fats and oils, reducing the rate of. It is also used as preservative in pharmaceuticals and cosmetics. Ascorbic acid 6-palmitate has antioxidant and antiproliferative activities. It scavenges hydroxyl radicals in cell-free assays and inhibits lipid peroxidation. It has been shown that despite its antioxidant properties, ascorbic acid 6-palmitate promotes LPO, JNK activation and cytotoxicity following UVB irradiation. Ascorbic acid 6-palmitate effectively inhibited anthrax cytotoxic protease and blocks proteolytic activities of host furin, cathepsin B and caspases that mediate toxin's lethality in cells. It is broad-spectrum and reduces cellular sensitivity to other bacterial toxins that require the same host proteases.