bs-75809C

DATASHEET

Formulation Solid

Storage: Stable for 2 years after receipt when stored at -20°C.

Product Information:

CAS Number: 172227-59-7

Molecular formula: C20H20N2O5

Molecular weight: 368.38

Purity: >95% (HPCE)

Appearance: Solid.

Solubility: Soluble in water or DMSO.

InChiKey: RCZAYEHQRFPFSH-UHFFFAOYSA-N

SMILES: CC(=O)NC1=CC=C2C(=O)N(CC(O)=O)C(=O)C3=C2C1=CC=C3

Description:

The highly fluorescent label 4-acetylamino-1,8-naphthalimide-N-caproic acid has two fused benzene rings containing a closed anhydride ring and therefore is a flat and planar molecule which can easily intercalate or act as a groove binder with DNA/RNA sequences. For the study of in situ hydridization with complementary synthetic oligonucleotides (ODNs), tagging with non-radioactive labels has gained importance, not only for medical diagnostics or clinical genetics, but also detection and isolation of DNA for research purposes. The pentamethylene chain in 6 acts as a linker molecule and keeps the target at a reasonable distance to avoid direct interaction with oligonucleotides.