DATASHEET
Formulation
Solid
Storage:
Stable for 1 year after receipt when stored at +4°C.
Product Information:
CAS Number: 18791-21-4
Molecular formula: C27H32N4O8
Molecular weight: 540.6
Purity: >98% (1H-NMR, HPLC)
Appearance: Off-white solid.
Solubility: Soluble in DMSO, methanol, water, dichloromethane or acetone.
InChiKey: WHIKSLGSXKIHCA-IGCCMALHSA-N
SMILES: CC\C(C)=C1/OC(=O)[C@H](C)[C@H](O)[C@H](CC2=CC=CN=C2)NC(=O)[C@@H](NC(=O)C2=C(O)C=CC=N2)[C@@H](C)OC1=O
Description:
Cyclodepsipeptide antibiotic. Unusual 12-membered macrocyclic depsipeptide comprises three unique subunits incorporating two substituted pyridines. Potent antitubercular agent. Inhibitor of NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis. Shown to be active against isoniazid-resistant mycobacteria.