DATASHEET
Formulation
Solid
Storage:
Stable for 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Product Information:
CAS Number: 55038-27-2
Molecular formula: C20H28O3
Molecular weight: 316.4
Purity: >97% (HPLC)
Appearance: White to off-white solid.
Solubility: Soluble in methanol or dichloromethane.
InChiKey: CGAKBBMRMLAYMY-YRWNJAEKSA-N
SMILES: [H][C@@]12OC(=O)C(C)=C1CC\C(C)=C\CC[C@]1(C)O[C@H]1CCC(C)=C2
Description:
Marine cembranoid diterpene. Anticancer agent. Inhibits in vivo skin carcinogenesis induced by NOR-1 and TPA. Decreases membrane permeability towards Ca2+, increases degradation of PLA and PLC and decreases levels of COX-2, inhibiting the tumor formation in melanoma models. Cell migration inhibitor in selected cancer cell lines. May be a phosphofructokinase inhibitor. Acetylcholine esterase and ATPase inhibitor. Ichthyotoxin. Tumorigenesis and JB6 cell transformation inhibitor.