bs-75714C
[Life Science]
Concanamycin B (high purity)
DATASHEET
Formulation Solid
Storage: Stable for 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Product Information:
CAS Number: 81552-33-2
Molecular formula: C45H73NO14
Molecular weight: 852.1
Purity: >98% (HPLC)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO, chloroform, acetonitrile or methanol; insoluble in water.
InChiKey: AQXXGIBOZQZSAT-UZYXLCJWSA-N
SMILES: [H][C@@]1(C[C@@H](O)[C@H](OC(N)=O)[C@@H](C)O1)O[C@@H]1C[C@@](O)(O[C@H](\C=C\C)[C@H]1C)[C@@H](C)[C@H](O)[C@H](C)[C@]1([H])OC(=O)\C(OC)=C\C(\C)=C\[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)[C@H](C)CC(C)=C\C=C\[C@@H]1OC
Molecular formula: C45H73NO14
Molecular weight: 852.1
Purity: >98% (HPLC)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO, chloroform, acetonitrile or methanol; insoluble in water.
InChiKey: AQXXGIBOZQZSAT-UZYXLCJWSA-N
SMILES: [H][C@@]1(C[C@@H](O)[C@H](OC(N)=O)[C@@H](C)O1)O[C@@H]1C[C@@](O)(O[C@H](\C=C\C)[C@H]1C)[C@@H](C)[C@H](O)[C@H](C)[C@]1([H])OC(=O)\C(OC)=C\C(\C)=C\[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)[C@H](C)CC(C)=C\C=C\[C@@H]1OC
Description:
Antibiotic. Exhibits similar activity as concanamycin A (Prod. No. bs-75709C) and concanamycin C (Prod. No. bs-75715C). Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Suppresses bone resorption. Inhibits proliferation of mouse splenic lymphocytes. Antifungal and larvicidal.
Size: 25ug,100ug,500ug,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.