bs-75700C
[Life Science]
Geldanamycin
DATASHEET
Formulation Solid
Storage: Stable for 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Product Information:
CAS Number: 30562-34-6
Molecular formula: C29H40N2O9
Molecular weight: 560.6
Purity: >98% (HPLC)
Appearance: Yellow solid.
Solubility: Soluble in methanol or DMSO; insoluble in water.
InChiKey: QTQAWLPCGQOSGP-GAEFGYQESA-N
SMILES: CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)\C(C)=C\C=C/[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)C2=O
Molecular formula: C29H40N2O9
Molecular weight: 560.6
Purity: >98% (HPLC)
Appearance: Yellow solid.
Solubility: Soluble in methanol or DMSO; insoluble in water.
InChiKey: QTQAWLPCGQOSGP-GAEFGYQESA-N
SMILES: CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)\C(C)=C\C=C/[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)C2=O
Description:
Antibiotic. Potent antitumor compound. pp60src tyrosine kinase inhibitor. Inhibits c-mycgene expression in murine lymphoblastoma cells. Inhibits the transforming activity of abl, erbB, fps, src and yes. Binds specifically to heat shock protein 90 (HSP90) and to its endoplasmic reticulum homolog GP96 (GRP94). Destabilizes several oncogene and proto-oncogene products. Potent nuclear hormone receptor family inhibitor.
Size: 100ug,500ug,1mg,5mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.