DATASHEET
Formulation
Solid
Storage:
Stable for 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Product Information:
CAS Number: 1403-36-7
Molecular formula: C31H30N6O6S4
Molecular weight: 710.9
Purity: >98% (HPLC)
Appearance: Off-white to fawn solid.
Solubility: Soluble in DMSO, ethyl acetate or pyridine; fairly soluble in methanol or 100% ethanol; insoluble in water.
InChiKey: ZRZWBWPDBOVIGQ-OKMJTBRXSA-N
SMILES: [H][C@]12NC3=CC=CC=C3[C@]1(C[C@]13SS[C@@](CO)(N(C)C1=O)C(=O)N23)N1C=C(C[C@]23SS[C@@](CO)(N(C)C2=O)C(=O)N3C)C2=CC=CC=C12
Description:
Anticancer antibiotic. Inhibitor of HIF-1 formation by disrupting the binding of p300 to both HIF-1alpha and HIF-2alpha. Histone H3K9 methyltransferases G9a and Suv39h inhibitor. Tumor growth inhibitor. Angiogenesis inhibitor. Potent immunosuppressor. Antibacterial and antifungal. Strong inducer of retinal pigment epithelium (RPE).