DATASHEET
Formulation
Solid
Storage:
Stable for 1 year after receipt when stored at -20°C. Stock solutions are stable for 3 months when stored at -20°C. After reconstitution, prepare aliquots and store at -20°C.
Product Information:
CAS Number: 93908-02-2
Molecular formula: C27H21Cl2N3O7
Molecular weight: 570.4
Purity: >98% (HPLC)
Appearance: Yellow solid.
Solubility: Soluble in DMSO.
InChiKey: QEHOIJJIZXRMAN-UMHCKEELSA-N
SMILES: COC1C(O)C(O)C(OC1CO)N1C2=C3NC4=C(C=CC=C4Cl)C3=C3C(=O)NC(=O)C3=C2C2=C1C(Cl)=CC=C2
Description:
Antibiotic. Structurally similar to staurosporine. Selective activity against several cancer cell lines. DNA intercalator, resulting in catalytic inhibition of topoisomerases I. Shows significant antitumor properties in vitro (IC50 = 480 nM against mouse B16 melanoma cells and IC50 = 500 nM against P388 leukemia cells). Does not show any inhibitory activity against protein kinases.
Size:
1mg,250 ug, 250 ug,
Applications:
Life Science()
For research use only. Not intended for diagnostic or therapeutic use.