bs-75674C
[Life Science]
Bafilomycin C1
DATASHEET
Formulation Powder
Storage: Stable for 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Product Information:
CAS Number: 88979-61-7
Molecular formula: C39H60O12
Molecular weight: 720.9
Purity: >98% (HPLC)
Appearance: Yellow powder.
Solubility: Soluble in 100% ethanol, methanol, DMSO or dimethyl formamide.
InChiKey: WUDBXVQNMOTFEE-WSNZTHDZSA-N
SMILES: [H][C@@]1(OC(=O)\C(OC)=C\C(\C)=C\[C@@H](C)[C@@H](O)[C@@H](C)C\C(C)=C\C=C/[C@@H]1OC)[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](OC(=O)\C=C\C(O)=O)[C@H](C)[C@H](O1)C(C)C
Molecular formula: C39H60O12
Molecular weight: 720.9
Purity: >98% (HPLC)
Appearance: Yellow powder.
Solubility: Soluble in 100% ethanol, methanol, DMSO or dimethyl formamide.
InChiKey: WUDBXVQNMOTFEE-WSNZTHDZSA-N
SMILES: [H][C@@]1(OC(=O)\C(OC)=C\C(\C)=C\[C@@H](C)[C@@H](O)[C@@H](C)C\C(C)=C\C=C/[C@@H]1OC)[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](OC(=O)\C=C\C(O)=O)[C@H](C)[C@H](O1)C(C)C
Description:
Antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antibacterial, insecticidal and anthelmintic. Antifungal activity, especially against C. albicans. Potential anti-osteoporotic agent in treating bone lytic diseases. Neuroprotection inducer. Cytotoxic activity against SMMC7721 HCC cells. Potential candidate for hepatic carcinoma chemotherapy.
Size: 1mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.