bs-75578C
[Life Science]
UK 5099
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 56396-35-1
Molecular formula: C18H12N2O2
Molecular weight: 288.3
Purity: >98% (HPLC)
Appearance: Off-white to yellow solid.
Solubility: Soluble in DMSO (20mg/ml) or DMF (10mg/ml). Sparingly soluble in aqueous buffers.
InChiKey: BIZNHCWFGNKBBZ-JLHYYAGUSA-N
SMILES: N#C/C(C(O)=O)=C\C1=CN(C2=CC=CC=C2)C3=CC=CC=C31
Molecular formula: C18H12N2O2
Molecular weight: 288.3
Purity: >98% (HPLC)
Appearance: Off-white to yellow solid.
Solubility: Soluble in DMSO (20mg/ml) or DMF (10mg/ml). Sparingly soluble in aqueous buffers.
InChiKey: BIZNHCWFGNKBBZ-JLHYYAGUSA-N
SMILES: N#C/C(C(O)=O)=C\C1=CN(C2=CC=CC=C2)C3=CC=CC=C31
Description:
Potent and specific inhibitor of the mitochondrial pyruvate carrier (MPC), blocking pyruvate from entering the mitochondria, consequently promoting lactate production. Inhibitor of tricarboxylic acid (TCA) cycle. Plasma membrane monocarboxylate transporters (MCTs) inhibitor, but with Ki values some two or three orders of magnitude higher than those for the inhibition of the MPC. Inhibits mitochondrial lactate and pyruvate transport. Decreases glycolysis. Useful agent for immunometabolism research.
Size: 1mg,5mg,10mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.