DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 1113-59-3
Molecular formula: C3H3BrO3
Molecular weight: 167
Purity: >98%
Appearance: White to off-white solid.
Solubility: Soluble in water (50mg/ml).
InChiKey: PRRZDZJYSJLDBS-UHFFFAOYSA-N
SMILES: O=C(CBr)C(O)=O
Description:
Cell permeable pyruvic acid derivative. Hexokinase II (HK2) inhibitor. Useful agent for immunometabolism research. Antitumor agent. Inhibits the rate limiting step of glycolysis and effectively suppress tumor survival in vitro and in vivo. Displays potent cytotoxic activity against cancer cells with mitochondrial respiratory defects and cells in hypoxic environment. Antifungal agent (anticryptococcal). Also used as affinity label for cysteine residues and cross-linker between nucleic acids and proteins.